Exspot Dog Spot-On 6Pip 2Ml 715Mg/Ml

EXSPOT 2 ML 6 PIPETTE  

EXSPOT

Pharmacotherapeutic Category

Topical ectoparasiticides.

Active Ingredients

Permethrin.

Excipients

Propylene glycol, Monomethyl Ether (Dowanol).

Indications

Treatment of ticks (Rhipicephalus sanguineus, Ixodes ricinus, Dermacentor variabilis, Amblyomma americanum), sandflies (Phlebotomus perniciosus, Lutzomya cruzi, L. corumbaensis), mosquitoes (Aedes aegypti, A. taeniorhynchus), flies (Stomoxys calcitrans and Musca domestica), fleas (Ctenocephalides felis and C. canis), and lice in dogs. The regular use of EXSPOT, at monthly intervals, eliminates ticks, sandflies, mosquitoes, flies, fleas, and lice and ensures protection against reinfestation for up to 4 weeks.

Contraindications/side Effects

Do not use in puppies under 2 weeks of age. Do not use in cats. Avoid contact between cats and recently treated dogs. Do not use on sick or convalescent animals or those with extensive skin lesions. Do not use in animals with known hypersensitivity to the active ingredient or any of the excipients.

Administration/use Route

Topical.

Dosing

Dogs weighing between 2.5 kg and 14 kg: 1 pipette of 1 ml, equal to a maximum dose of permethrin of 286 mg/kg (dogs of 2.5 kg) and minimum of 51 mg/Kg (dogs of 14 kg). Dogs weighing between 15 and 29 Kg: 2 pipettes of 1 ml, equal to a maximum dose of permethrin of 95.3 mg/kg (dogs of 15 kg) and minimum of 49.3 mg/Kg (dogs of 29 kg), or alternatively, 1 pipette of 2 ml. Dogs weighing between 30 and 40 Kg: 3 pipettes of 1 ml, equal to a maximum dose of permethrin of 71.5 mg/kg (dogs of 30 kg) and minimum of 53.6 mg/Kg (dogs of 40 kg). Dogs weighing over 41 kg up to 55 kg: 2 pipettes of 2 ml, equal to a maximum dose of permethrin of 69.7 mg/kg (dogs of 41 kg) and minimum of 52 mg/Kg (dogs of 55 kg). For use only as a spot-on. Open the bag and take the pipette. For easier application, the animal should be kept standing. With one hand hold the pipette upright, away from the face and break the top end of the pipette to open it, bending and folding it back on itself. Part the hair until the skin is visible and place the tip of the pipette directly on the dog's skin, applying the product according to the following instructions. Firmly press the pipettes until their entire contents are emptied directly onto the skin of the back. Apply the contents of individual pipettes at four different points along the back line, starting from the area between the two shoulder blades to the area of the rump, at the base of the tail, ensuring that the product does not run onto the hair. The interval between treatments will depend on the severity of the infestation and the parasite. Regular use, at monthly intervals, eliminates ticks, sandflies, mosquitoes, flies, fleas, and lice and provides protection for up to 4 weeks against reinfestation. The use of non-medicated shampoos prior to the application of this product does not negatively affect the effectiveness of the product. If the dog undergoes bathing and sponging, the period of protection is reduced, depending on the amount of water that comes into contact with the skin. It can be applied at intervals of no less than 2 weeks without causing side effects or symptoms of poisoning. To reduce reinfestations, it is recommended to treat all dogs in the household and all cohabiting pets in the same environment with an appropriate product. It is also advisable to carry out adequate environmental treatment against adult fleas and their developing stages (immature forms).

Storage

Protect from light. Store at a temperature below 25 degrees C.

Warnings

Treated dogs must not enter water until 12 hours have passed since treatment. It must be applied directly to the skin. Avoid application on the hair. As a precautionary measure, it is not recommended to perform the treatment more than 4 times in 3 months. Avoid contact of the product with the eyes and mouth of the treated dogs. Avoid treated animals, or animals in contact with them, licking the application site. It is extremely toxic to cats and may even be fatal, due to cats' inability to metabolize permethrin. Avoid letting cats lick the application site of treated dogs. If this occurs, contact a veterinarian immediately. Treated dogs must be kept away from cats until the application site has dried. Special precautions for those administering the product to animals: avoid direct contact of the contents with hands, use protective gloves. Avoid contact with skin, eyes, and mucous membranes. After each application and in case of contact with the skin, wash hands thoroughly with water and soap. In the case of multiple applications (for example in kennels), it is advisable for operators to wear neoprene or nitrile protective gloves with a minimum thickness of 0.3 mm. Do not come into contact with the application area within 3-6 hours after treatment. It is preferable to perform the treatment in the evening. Treated dogs must not sleep with people, especially children. Do not eat, drink, or smoke during the use of the product. In case of ingestion, consult a doctor and show him the container and the label. Do not contaminate food, beverages, or containers meant for them. For external use only. People with known hypersensitivity to the active ingredient should avoid contact with the veterinary medicine. Treated animals should not be handled, especially by children, until the application site is dry. Overdose: the clinical signs of overdose are typical of pyrethroid toxicity and are the same as those already described. There is no specific antidote for pyrethroid poisoning.

Withdrawal Time

Not applicable.

Target Species

Dogs.

Interactions

Do not use simultaneously with other antiparasitics.

Side Effects

The active ingredient permethrin contained in the product may cause phenomena of skin hypersensitivity such as itching, dermatitis, eczema, rashes, hair loss, and redness at the application site. These symptoms are often accompanied by hyperactivity in treated animals. In very rare cases, dogs may show hypersalivation, gastrointestinal symptoms (decreased appetite, anorexia, diarrhea, vomiting), neurological symptoms (lethargy, incoordination, muscle tremors, disorientation, hyperesthesia, paresis, ataxia), and behavioral changes (restlessness, urinary incontinence, aggression). In such cases, a complete wash (bath) of the animal is recommended. The excipient contained in the product usually has good local tolerability and only in exceptional cases can induce skin hypersensitization.

Pregnancy and Lactation

Do not use in lactating female dogs. In pregnant dogs, use only according to the risk/benefit assessment.