NORFLO 30CPR

NORFLO

Dietary supplement based on Meriva (phospholipid curcuma) useful as an adjunct to counteract degenerative processes related to age and/or in conjunction with specific pathological conditions.
Curcumin is a biologically active component of turmeric; it is extracted and concentrated from it. Curcumin is effective as an antioxidant and as a physiological modulator of inflammatory processes related to oxidation. The Meriva contained in the product significantly improves the absorption of curcumin compared to standard extracts and therefore reaches higher levels of active principles in the bloodstream.

Ingredients

	per 1 tablet	per 2 tablets
Meriva    of which turmeric extract        Soy Phospholipids	100 mg 200 mg	200 mg 400 mg

Directions for use
It is recommended to take 1-2 rapid-disintegration tablets per day with meals with a sip of water.

Warnings
Keep out of reach of children under 3 years.
Do not exceed the recommended daily dose.
Supplements should not be used as a substitute for a varied diet.
Do not use during pregnancy.

Format
Box of 30 rapid-disintegration tablets.

Bibliography
  -   Kidd, P. M. Bioavailability and activity of Phytosome complexes from botanical polyphenols: the silymarin, curcumin, green tea, and grape seed extracts. Alt. Med. Rev. 2009, 14, 226-246.
  -   Aggarwal, B. B.; Sung, B. Pharmacological basis for the role of curcumin in chronic diseases: an age-old spice with modern targets. Trends Pharmacol. Sci. 2009, 30, 85-94.
  -   Jurenka, J. S. Anti-inflammatory properties of curcumin, a major constituent of Curcuma longa: a review of preclinical and clinical research. Altern. Med. Rev. 2009, 14, 141-153.
  -   Anand, P.; Kunnumakkara, A. B.; Newman, R. A.; Aggarwal, B. B. Bioavailability of curcumin: Problems and promises. Mol. Pharm. 2007, 4, 807-818.
  -   Marczylo TH, Verschoyle RD, Cooke DN, Morazzoni P, Steward WP,Gescher AJ., Comparison of systemic availability of curcumin with that of curcumin formulated with phosphatidylcholine, Cancer Chemother Pharmacol. 2007 Jul;60(2):171-7.Epub 2006 Oct 19.
  -   Cuomo, J., et al., Comparative Absorption of a Standardized Curcuminoid Mixture and Its Lecithin Formulation. J Nat Prod, 2011.
  -   Belcaro G., Cesarone M. R., Dugall M. et al., Product-evaluation registry of Meriva, a curcumin-phosphatidylcholine complex, for the complementary management of osteoarthritis, Panminerva Medica 2010 June;52(2 Suppl1).55-62.
  -   Belcaro G., Cesarone M.R., Dugall M. et al., Efficacy and Safety of Meriva®, a Curcumin-phosphatidylcholine Complex, during Extended Administration in Osteoarthritis Patients Altern Med Rev. 2010 Dec;15(4):337-44.
  -   Allegri P., Mastromarino A. Management of chronic anterior uveitis relapses: efficacy of treatment with oral phospholipidic curcumin. Long-term follow-up, Clinical Ophthalmology 2010, 4, 1-6
  -   Steigerwalt, R., et al., Meriva(R), a lecithinized curcumin delivery system, in diabetic microangiopathy and retinopathy. Panminerva Med, 2012. 54(1Suppl 4): p. 11-6.
  -   Appendino G. et al.,""Potential role of curcumin phytosome (Meriva) in controlling the evolution of diabetic microangiopathy. A pilot study"" Panminerva Medica 2011, 53 (3 Suppl 1):43-90